Is edetate disodium toxic?
The FDA has approved calcium disodium EDTA as a safe food additive but has set limitations on the amount of the substance a food can contain (2).
Is edetate disodium safe for skin?
In several studies, the Cosmetics Review Board has found that as used in cosmetics products, disodium EDTA is safe. It was determined that in the concentrations used in commercial cosmetics, it is not a skin sensitizer nor a carcinogen, and does not penetrate through skin.
What are the side effects of disodium EDTA?
Edetate disodium side effects
- nausea, vomiting, diarrhea;
- numbness or tingling (especially around your mouth);
- headache; or.
- pain, redness, or swelling where the needle is placed.
Is EDTA harmful in cosmetics?
Facts: EDTA is safe for use in cosmetics, and for decades the data is well-reported. At the concentration level as it is used in our products, EDTA is a well-tolerated ingredient and allergic cases are very rare.
Is edetate disodium a preservative?
Edetate disodium (EDTA) and benzalkonium chloride (BAC) are often present as preservative or stabilizing agents in nebulizer solutions used to treat asthma and chronic obstructive pulmonary disease.
What is edetate disodium used for?
EDETATE DISODIUM, EDTA (ED uh teyt di SOE dee um) EDTA binds with calcium and some heavy metals in the body. It is used to treat calcium overload. It is also used to treat irregular heart beats caused by too much digitalis (digoxin or digitoxin).
Is edetate disodium same as EDTA?
Edetate calcium disodium ([CH2N(CH2CO2H)2]2, also known as calcium EDTA or edetate disodium) is a chelating agent, and is capable of removing a heavy metal, such as lead or mercury, from the blood circulatory system. Edetate calcium disodium is used to treat lead poisoning.
What is disodium edetate in eye drops?
Edetate disodium is used to bind chemicals called proteinases and metalloproteinases that break down the clear part of the eye (cornea) and to remove calcium deposits in the eye.
Is EDTA toxic to humans?
EDTA can cause abdominal cramps, nausea, vomiting, diarrhea, headache, low blood pressure, skin problems, and fever. It is UNSAFE to use more than 3 grams of EDTA per day, or to take it longer than 5 to 7 days. Too much can cause kidney damage, dangerously low calcium levels, and death.
Is disodium EDTA safe for eyes?
Conclusions: These data show that the new preservative NIG/EDTA, at doses known to have effective antimicrobial properties, has a very low toxicity on corneal cells, and so it can be safely used in multi-dose eye drops.