What is the specific antidote for organochlorine exposure?
No specific antidotes are available for organochlorine poisoning. Decontamination may be indicated to prevent continued absorption, as well as exposure of health care personnel.
Is lindane neurotoxic?
Neurotoxicity is the most frequently observed adverse effect of lindane due to its predilection for the lipid-rich white matter of the brain. Lindane levels in the brain have been found to be 10 times greater than in blood following a single topical application of 1% lindane lotion.
Why is lindane toxic?
Lindane is quite toxic to humans. The acute (short-term) effects of lindane through inhalation exposure in humans consist of irritation of the nose and throat and effects on the blood.
Why lindane was discontinued?
FDA has restricted the use of these products since the 2002 RED. Use in foreign countries may result in exposures in the U.S. because lindane can migrate over long distances through air, water, and sediment. Lindane is recognized internationally as a toxic, persistent, and bio-accumulative pesticide.
Which known medical condition is contraindicated with the use of lindane?
Lindane Lotion is also contraindicated for patients with crusted (Norwegian) scabies and other skin conditions (e.g., atopic dermatitis, psoriasis) that may increase systemic absorption of the drug.
Is lindane banned in US?
A highly toxic pesticide that is one of the last such holdouts from the 1950s is being banned in the United States after a lengthy review by the Environmental Protection Agency.
Is lindane still used?
The only remaining U.S. use of lindane is for prescription shampoos and lotion treatments for head lice and scabies, which are regulated by the Food and Drug Administration, not the EPA. Lindane prescriptions have been banned in California since 2002, and most U.S. doctors no longer prescribe them.
Where is lindane banned?
Lindane has been used on U.S. crops since 1950. The EPA heavily restricted it in 1983, limiting its use to grain seeds to prevent pests from eating the plants. It is banned in the European Union, Japan and several other Asian countries, South Africa, and much of Latin and South America.
Is lindane lotion still available?
Lindane Lotion – Drug Discontinuation — The decision to discontinue Lindane 1% lotion was for business reasons. — The discontinuation of Lindane 1% lotion was effective as of June 2, 2016. patients who cannot tolerate other approved therapies, or have failed treatment with other approved therapies.
How does atropine help organophosphate toxicity?
Atropine is administered intravenously to restore adequate cardiorespiratory function rapidly – a process often termed ‘atropinzation’. It is used to reverse bradycardia and improve systolic blood pressure to greater than 80 mmHg.
What is the antidote for organophosphate toxicity quizlet?
Activated charcoal, provided given within two hours of poisoning with OP, allows to reduce severity of toxicity.
Which clients can safely receive lindane?
Lindane topical lotion is used to treat scabies. This medicine is for use in adults and children who weigh at least 110 pounds….You should not use lindane topical if you are allergic to it, or if you have:
- an uncontrolled seizure disorder;
- crusted scabies; or.
- other skin conditions such as eczema or psoriasis.
Is lindane safe for children?
Lindane lotion should be used with caution for infants, children, the elderly, and individuals with other skin conditions (e.g, atopic dermatitis, psoriasis) and in those who weigh < 110 lbs (50 kg) as they may be at risk of serious neurotoxicity.
Can you still buy lindane?
Lindane shampoo is used to treat only lice infestations. Lindane is available only with your doctor’s prescription. This product is available in the following dosage forms: Shampoo.
When was lindane banned in the US?
In 2002, California banned pharmaceutical use of lindane because of concerns about water quality, as lindane treatment for head lice and scabies was found to be a significant factor adversely affecting wastewater quality.
Is lindane lotion safe?
What is lindane and is it safe?
“Lindane is clearly a very hazardous pesticide,” says Michael Hansen, Ph. D., a senior scientist at Consumer Reports. “It can be absorbed through the scalp, and we are particularly concerned about its use, especially in treating children. ”
Is lindane toxic to breast-feeding mothers?
Lindane is lipophilic and is present in human breast milk, but exact quantities are not known. There may be a risk of toxicity if Lindane is ingested from breast milk, or from skin absorption from mother to baby in the course of breast-feeding when Lindane Lotion is applied topically to the chest area.
What is the active ingredient in lindane?
In addition to the active ingredient, Lindane, it contains 2-amino-2-methyl-1-propanol, carrageenan, cetyl alcohol, cocoa butter, glyceryl monostearate, methylparaben, propylene glycol, propylparaben, purified water, stearic acid and trolamine to form a lotion. The pH range is between 6.5 and 8.5.
What is lindane lotion used for?
What is Lindane Lotion? Lindane Lotion is a medicine that is used to treat scabies. It kills scabies and their eggs. Scabies are very small bugs (mites) that crawl under your skin, lay eggs, and cause severe itching. Lindane Lotion goes through your skin and kills the scabies and their eggs.