What ingredients are in topiramate?
TOPAMAX® Sprinkle Capsules contain topiramate-coated beads in a hard gelatin capsule. The inactive ingredients are black pharmaceutical ink, cellulose acetate, gelatin, povidone, sodium lauryl sulfate, sorbitan monolaurate, sugar spheres (sucrose and starch) and titanium dioxide.
Does Topamax cause electrolyte imbalance?
Topiramate is a commonly used medication with several indications including migraines, myoclonic jerks and seizures. It has been reported to cause renal tubular acidosis and severe electrolyte abnormalities, which in turn predispose patients to neuropathology via renal concentration defects and osmotic shifts.
Why should you not drink on topiramate?
Alcohol and topiramate both act as brain depressants, which can impair your thinking and coordination. Risks of drinking alcohol while taking topiramate include mental and psychological side effects, including confusion, dizziness, drowsiness, and depression.
What does Topamax do to potassium?
Topiramate belongs to the new class of neuromodulators, which has carbonic anhydrase inhibitor activity and been associated with renal calculi. It has also been shown to cause renal potassium wasting; however, it is generally clinically insignificant.
Does Topamax affect sodium levels?
Laboratory tests: Topiramate may decrease sodium bicarbonate levels and lead to metabolic acidosis. If you experience shallow, rapid breathing, unusual tiredness and loss of appetite, contact your doctor. Sodium bicarbonate levels should be monitored by your doctor with blood tests, while you are taking topiramate.
Can you drink coffee with Topamax?
Can you drink caffeine with Topamax? Topamax can increase caffeine’s excretion rate, which may reduce its efficacy in the body, but it’s generally a safe combination.
Can you drink with topiramate?
It’s best not to drink too much alcohol while taking topiramate. It may make you feel sleepy or tired, and alcohol and hangovers can bring on seizures in some people with epilepsy.
What happens if you drink while taking topiramate?
Drinking alcohol while taking Topamax can increase the chance of you experiencing side effects. The combination can cause excessive sleep, confusion, difficulty with memory and difficulty speaking. Don’t drive or operate machinery while on Topamax (topiramate), especially if you’ve consumed alcohol.
Can you drink while taking topiramate?
Does Topamax make you pee a lot?
Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: signs of kidney stones (such as severe back/side/abdominal/groin pain, fever, chills, painful/frequent urination, bloody/pink urine).
What vitamins should I take with Topamax?
Replenish Depleted Nutrients
- Biotin.
- Calcium.
- L-Carnitine.
- Vitamin A.
- Vitamin B12.
- Vitamin D.
- Vitamin E.
Will topiramate show up on a drug test?
Conclusion: Topiramate treatment may well be a cause of false positives in DSTs, and its presence should be taken into consideration when screening for hypercortisolism.
Can I just stop taking Topamax 25 mg?
You should not stop taking Topamax suddenly unless your doctor has told you to stop. Stopping suddenly may increase the risk of seizures or other withdrawal side effects. If you have epilepsy and you stop taking Topamax suddenly, you may have seizures that do not stop.
Can you take vitamin D with topiramate?
Conclusion: A combination of topiramate and vitamin D3 might be considered safe and more effective than topiramate alone in the prophylaxis of pediatric migraine.
How many mg of topiramate are in a tablet?
Topiramate tablets, USP are available as 25 mg, 50 mg, 100 mg, and 200 mg round tablets for oral administration. Topiramate is a white crystalline powder with a bitter taste. Topiramate is most soluble in alkaline solutions containing sodium hydroxide or sodium phosphate and having a pH of 9 to 10.
What are the signs and symptoms of an overdose of topiramate?
Signs and symptoms included convulsions, drowsiness, speech disturbance, blurred vision, diplopia, impaired mentation, lethargy, abnormal coordination, stupor, hypotension, abdominal pain, agitation, dizziness and depression. The clinical consequences were not severe in most cases, but deaths have been reported after overdoses involving Topiramate.
What are the different forms of topiramate?
Dosage Forms and Strengths. Topiramate tablets USP are available in the following strengths and colors: 25 mg, White colored, circular, biconvex film-coated tablets, debossed with “122” on one side and “C” on the other side.
What is the mechanism of action of topiramate?
Topiramate is a carbonic anhydrase inhibitor. Carbonic anhydrase inhibitors can promote stone formation by reducing urinary citrate excretion and by increasing urinary pH [see Warnings and Precautions ( 5.4 )].