Is edema intracellular or interstitial?
The definition of edema is a swelling due to the expansion of interstitial fluid volume in tissues or an organ. Several clinical conditions present with edema, making it a critical clinical feature for diagnostic medicine.
What causes intracellular edema?
Impairment of energy metabolism caused by hypoxia leads to intracellular oedema, because Na+ accumulates in the cells when ATP is no longer available for the sodium pump.
Is edema interstitial fluid?
Edema is defined as a palpable swelling produced by expansion of the interstitial fluid volume; when massive and generalized, the excess fluid accumulation is called anasarca.
What is the pathophysiology of pitting edema?
Pathophysiology of Edema Edema results from increased movement of fluid from the intravascular to the interstitial space or decreased movement of water from the interstitium into the capillaries or lymphatic vessels. The mechanism involves one or more of the following: Increased capillary hydrostatic pressure.
Is pitting edema intracellular or extracellular?
In most instances, edema occurs mainly in the extracellular fluid compartment, but it can involve intracellular fluid as well.
In which extracellular fluid compartment does edema occur?
When the fluid volume within the interstitial compartment (space between the cells and blood vessels) increases, this compartment increases in size leading to tissue swelling (i.e., edema).
What is cellular edema?
1. An accumulation of an excessive amount of watery fluid in cells or intercellular tissues. 2. At the gross level, used to describe the physical sign commonly likened to swelling or increased girth that often accompanies the accumulation of fluid in a body part, most often a limb.
What kind of fluid is edema?
Edema happens when your small blood vessels leak fluid into nearby tissues. That extra fluid builds up, which makes the tissue swell. It can happen almost anywhere in the body.
What fluid causes edema?
Edema occurs when tiny blood vessels in your body (capillaries) leak fluid. The fluid builds up in surrounding tissues, leading to swelling.
What is intracellular fluid compartment?
Intracellular compartment The intracellular fluid (ICF) is all fluids contained inside the cells, which consists of cytosol and fluid in the cell nucleus. The cytosol is the matrix in which cellular organelles are suspended. The cytosol and organelles together compose the cytoplasm.
What is the interstitial fluid?
(IN-ter-STIH-shul FLOO-id) Fluid found in the spaces around cells. It comes from substances that leak out of blood capillaries (the smallest type of blood vessel). It helps bring oxygen and nutrients to cells and to remove waste products from them.
Why is cellular swelling reversible?
Cellular swelling (or cloudy swelling) may occur due to cellular hypoxia, which damages the sodium-potassium membrane pump; it is reversible when the cause is eliminated.
What is pitting edema?
Pitting edema is when a swollen part of your body has a dimple (or pit) after you press it for a few seconds. It can be a sign of a serious health issue.
What causes water retention in stomach?
What is ascites? Ascites is the medical term for a buildup of fluid in the abdomen. It can happen when the blood pressure of the portal vein — which runs from the digestive organs to the liver — gets too high. This increased pressure reduces kidney and liver function, causing fluid to accumulate.
What causes fluid retention in the legs?
Swelling in the ankles, feet and legs is often caused by a build-up of fluid in these areas, called oedema. Oedema is usually caused by: standing or sitting in the same position for too long. eating too much salty food.
What are the examples of intracellular fluid?
Intracellular fluid represents around 40% of total human body weight and is comprised of water, dissolved electrolytes, and proteins. Some of the common electrolytes found in intracellular fluid include phosphate (PO4− P O 4 − ), magnesium (Mg2+ M g 2 + ), and potassium (K+ ).
What is intracellular fluid called?
cytosol
Intracellular fluid is often referred to as cytosol when discussing cellular functions. The cytosol and the organelles and molecules contained within are referred to collectively as the cytoplasm.