How effective is docetaxel for breast cancer?
Docetaxel (Taxotere) is among the most active agents for metastatic breastcancer. Initial phase II studies of docetaxel administered at 100 mg/m² showedresponse rates of 53% to 68% in patients previously treated withchemotherapy. [2-6] A multicenter phase II study of docetaxel at 75 mg/m² showeda response rate of 52%.
How toxic is docetaxel?
Concerning the toxicity profile of docetaxel, our experience is characterized by a predominance of hematological adverse events (15.9%), mainly anemia (11.6%) and neutropenia (8.5%).
Can docetaxel be given weekly?
The taxanes, paclitaxel and docetaxel, represent the standard of care for the treatment of these patients. Among the various schedules, docetaxel can be administered weekly, achieving similar efficacy results with lower toxicity compared with conventional schedules.
Can Taxotere be given weekly?
and stopped in one patient due to painful nail toxicity. Conclusion: Weekly administration of docetaxel at a dose of 35 mg/m2 is effective and of low toxicity in patients with metastatic breast cancer.
How long do you take Phesgo?
If you are taking PHESGO for early breast cancer, you will take it every 3 weeks for a total of 1 year (up to 18 cycles) unless side effects become too difficult to manage or the cancer comes back sooner.
How effective is PHESGO?
Phesgo is as effective at treating breast cancer as the individual medicines given into a vein. Because it is given under the skin, it may be more convenient for patients and is less invasive and faster than being given the medicines by infusion.
How often is PHESGO given?
Administer PHESGO every 3 weeks for a total of 1 year (up to 18 cycles) or until disease recurrence or unmanageable toxicity, whichever occurs first, as part of a complete regimen for early breast cancer, including standard anthracycline- and/or taxane-based chemotherapy.
Is docetaxel the same as Taxol?
Taxol is the name under which the drug paclitaxel is sold, while Taxotere is a rebranding of the drug docetaxel. Both of these drugs fall under the category of “taxanes,” which is a class of chemicals derived from the bark of the Pacific yew tree.
How long can you take PHESGO?
Is PHESGO better than Herceptin?
The study also looked at how safe the drug was and if it worked on the cancer. In this study, no major difference was seen in the amount of medicine that went into the bloodstream with PHESGO compared to PERJETA + Herceptin. The combined results of the study showed no major difference is expected in how it works.