What is NLPHL?
Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare type of Hodgkin lymphoma (HL) that tends to grow more slowly than classic HL (cHL).
Is NLPHL curable?
NLPHL is curable, but people may relapse years after complete remission. Very rarely, NLPHL can progress into an aggressive type of NHL called diffuse large B-cell lymphoma. NLPHL is uncommon, only accounting for 5 percent of all cases of HL.
What are the symptoms of NLPHL?
The most common symptom of NLPHL is a lump or lumps. These typically develop in your neck, armpits or groin. They can develop in other places, too. The lumps are caused by lymphoma cells building up in your lymph nodes, which makes the lymph nodes swell.
How do you treat relapsed NLPHL?
In relapsed NLPHL, conventional chemotherapy, anti-CD20 antibodies, and radiotherapy represent active treatment modalities. Only patients with poor-risk characteristics such as early disease recurrence are candidates for aggressive salvage treatment with high-dose chemotherapy and autologous stem cell transplantation.
How many people have NLPHL?
Results: We identified 1,937 cases of NLPHL. The majority were younger than 65 years (86%), white (70%), male (67%), and diagnosed between 2001-2015 (85%), when rituximab was introduced. Of all cases, 1336 (69%) were classified as early stage.
What is the difference between lymphoma and Hodgkin’s disease?
Lymphoma is a form of cancer that affects the lymphocytes. The primary difference between Hodgkin and non-Hodgkin lymphoma is the type of lymphocyte that is affected. Hodgkin lymphoma is marked by the presence of Reed-Sternberg lymphocytes, which a physician can identify using a microscope.
How is Nlphl 2020 treated?
First-line treatment of stage IA NLPHL usually consists of limited-field radiotherapy alone. Patients with early-stage NLPHL other than stage IA and intermediate-stage disease mostly receive combined-modality treatment, whereas individuals with advanced NLPHL are treated with chemotherapy alone.
What is lymphocytic predominance?
A rare type of Hodgkin lymphoma (a cancer of the immune system). It is marked by the presence of lymphocyte-predominant cells, which used to be called popcorn cells. These cells are different from the typical Reed-Sternberg cells found in classic Hodgkin lymphoma.
Which type of Hodgkin’s is worse?
The type of chemotherapy you receive will depend on how aggressive the cancer is. “T-cell non-Hodgkin lymphomas tend to be more aggressive,” Strati says. “Whereas B-cell non-Hodgkin lymphomas may be more slow-growing.”
What is the ICD 10 code for nodular lymphocyte predominant Hodgkin’s lymphoma?
0 for Nodular lymphocyte predominant Hodgkin lymphoma is a medical classification as listed by WHO under the range – Malignant neoplasms .
Which is more curable Hodgkins or non-Hodgkin’s?
Hodgkin’s lymphoma is one of the most curable cancers. It typically has a better outlook than non-Hodgkin’s lymphoma.