What autoimmune diseases cause calcification?
The likelihood of developing calcinosis varies among the autoimmune connective tissue diseases, with systemic sclerosis and dermatomyositis being the most commonly associated.
Is calcinosis curable?
Often calcinosis cutis has no symptoms. But in some cases, it can be very painful. Treatments are available, including surgery, but the calcium lesions may recur.
Is calcinosis the same as calcification?
The deposition of calcium in the skin, subcutaneous tissue, muscles and visceral organs is known as calcinosis. This condition commonly occurs in the skin, where it is known as calcinosis cutis or cutaneous calcification.
How do you get calcinosis?
Calcinosis cutis happens when calcium gathers in your skin, muscles, tendons, connective tissue, and subcutaneous tissue — the innermost layer of your skin that contains fat. There are five types of calcinosis cutis, including: Dystrophic. Metastatic.
What causes calcification of the joints?
It is not known for sure what causes calcific tendonitis, but it’s believed that certain factors such as diabetes, thyroid disease, and a person’s genetics may play a role in the risk of developing calcific tendonitis.
Can calcinosis be removed?
Using surgery removal or laser removal also can damage or cause injury to the skin. This can cause your lesions to grow back. Other risks include slow wound healing and infection. Calcinosis cutis can be hard to manage and treat because there isn’t one treatment that works for everyone.
How do you get rid of calcium calcinosis?
Calcinosis cutis can be treated with drugs like calcium channel blockers, prednisone, warfarin, or colchicine that lower calcium levels or reduce inflammation. The lesions can be removed or reduced with surgery, laser therapy, or a procedure known as iontophoresis.
What does calcified mean in medical terms?
Calcification is a process in which calcium builds up in body tissue, causing the tissue to harden. This can be a normal or abnormal process.
What do calcium deposits indicate?
In medical terminology, such deposits of calcium and fatty material in the arteries is called atherosclerosis. Buildup of calcium deposits in the arteries increases the risk of coronary artery disease. People with elevated levels of calcium in their blood are much more susceptible to heart attacks and stroke.
What is subepidermal calcified nodule?
Subepidermal calcified nodule is an uncommon, but specific subtype of idiopathic calcinosis. It presents as an asymptomatic, solitary, yellow-white or erythematous filiform tumor. The most common location is on the head and neck region of male children. Serum calcium and phosphorus levels are normal …
What are the radiographic findings characteristic of gout?
Gout is definitively diagnosed on the basis of demonstration of urate crystals in aspirated synovial fluid, in the absence of another etiology for arthritis. Classic radiographic findings are highly suggestive (see Workup ).
What is the pathophysiology of subsidence of gout?
Subsidence of an acute gout attack results from multiple mechanisms, including the clearance of damaged neutrophils, change in the properties of urate crystals, and the production of anti-inflammatory cytokines such as IL-1 receptor antagonist (IL-1RA), IL-10, and transforming growth factor (TGF)-β.
What are the comorbidities of gout?
Certain comorbid conditions are associated with a higher incidence of gout, including the following [24, 25] : 1 Hypertension. 2 Diabetes mellitus. 3 Renal insufficiency. 4 Hypertriglyceridemia. 5 Hypercholesterolemia. 6 (more items)