Is pertuzumab and trastuzumab chemotherapy?
Perjeta (chemical name: pertuzumab) used in combination with Herceptin (chemical name: trastuzumab), another targeted therapy medicine, and Taxotere (chemical name: docetaxel), a type of chemotherapy, to treat HER2-positive, metastatic breast cancer that hasn’t been treated with either Herceptin or chemotherapy yet.
Why is pertuzumab and trastuzumab given together?
Pertuzumab was approved by the FDA in June 2012 for use in combination with trastuzumab and docetaxel for the treatment of patients with HER2-positive metastatic breast cancer without prior treatment with anti-HER2 therapy for metastatic disease.
What is trastuzumab pertuzumab based therapy?
Pertuzumab (Perjeta®) and trastuzumab are targeted therapy drugs used to treat breast cancer. They are usually given with chemotherapy.
Is pertuzumab a chemo?
Pertuzumab is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as an “antineoplastic agent and a monoclonal antibody”.
Is pertuzumab an immunotherapy?
Passive immunotherapy has provided several successful treatments for breast cancer. The current mainstay of passive immunotherapy includes trastuzumab, pertuzumab, and trastuzumab emtansine (T-DM1).
Do pertuzumab and trastuzumab cause hair loss?
Pertuzumab and trastuzumab do not usually cause people to lose their hair. Any hair loss caused by chemotherapy should be temporary and in most cases your hair will begin to grow back once your chemotherapy has ended.
Does pertuzumab cause skin and nail changes?
Nail Changes and Rash Your fingernails/toenails may become dark, brittle, or fall off. Keep your fingernails and toenails clean and dry.
Is pertuzumab a chemotherapy?
Is pertuzumab a chemo drug?
Will hair grow back while on Herceptin?
Your hair may thin but you’re unlikely to lose all your hair. This usually starts after your first or second cycle of treatment. It is almost always temporary and your hair will grow back when you finish your treatment.
What type of drug is trastuzumab?
Trastuzumab and pertuzumab are types of targeted cancer drugs called monoclonal antibodies. Monoclonal antibodies work by attaching to proteins on or in cancer cells. Human epidermal growth factor 2 (HER2) is a protein that makes cells grow and divide. Some cancers have large amounts of HER2 protein and are called HER2 positive cancers.
What is the role of pertuzumab in the treatment of metastatic cancer?
The addition of pertuzumab further improved upon results achieved with trastuzumab and chemotherapy, specifically extending overall survival in patients with metastatic disease, lessening the risk of recurrence when used in the adjuvant setting, and improving pathologic complete response rate when utilized in the neoadjuvant setting.
Can it be given as an infusion instead of pertuzumab?
It can be given in less time than pertuzumab or trastuzumab, which are given as infusions. For more information about pertuzumab and trastuzumab that may apply to pertuzumab, trastuzumab, and hyaluronidase-zzxf, see the Drug Information Summaries for Pertuzumab and Trastuzumab.
How do I get Started with trastuzumab?
Sometimes you can have trastuzumab as an injection under the skin. Some hospitals give the first dose of trastuzumab the day after you have pertuzumab. Your nurse gives you your chemotherapy after you have had your pertuzumab and trastuzumab. Your nurse, pharmacist or doctor will discuss your treatment plan with you.