What does heterogeneity mean on an MRI?
Heterogeneous refers to a structure with dissimilar components or elements, appearing irregular or variegated. For example, a dermoid cyst has heterogeneous attenuation on CT. It is the antonym for homogeneous, meaning a structure with similar components. Heterogenous refers to a structure having a foreign origin.
Does heterogeneous signal mean cancer?
Cancer is a heterogeneous disease. Practically from the moment pathologists first looked at human cancers under the microscope, they saw that differing histologic appearances could define distinct subtypes of cancers from the same primary site of origin.
What does it mean when a disease is heterogeneous?
A genetic or allelic heterogeneous condition is one where the same disease or condition can be caused, or contributed to, by varying different genes or alleles. In clinical trials and statistics the concepts of homogeneous and heterogeneous populations is important.
Does heterogeneous enhancement mean cancer?
Conclusion. Heterogeneous enhancement patterns of tumor-adjacent parenchyma at MR imaging are associated with the tumor necrosis signaling pathway and poor survival in breast cancer.
What does diffusely heterogeneous marrow signal mean?
4. This heterogeneous marrow signal most likely represents patchy conversion of red to yellow marrow that is a well-described normal variant seen predominantly in older adults.
Can you tell if a tumor is malignant from an MRI?
Using MRI, doctors can sometimes tell if a tumor is or isn’t cancer. MRI can also be used to look for signs that cancer may have metastasized (spread) from where it started to another part of the body. MRI images can also help doctors plan treatment such as surgery or radiation therapy.
What do you mean by heterogeneity?
Definition of heterogeneity : the quality or state of consisting of dissimilar or diverse elements : the quality or state of being heterogeneous cultural heterogeneity.
What causes heterogeneous?
Allelic heterogeneity occurs when different variants at a single gene locus cause the same or similar phenotypic expressions of a disease or condition. Locus heterogeneity occurs when variants at different gene loci cause the same or similar phenotypic expressions of a disease or condition.
Is heterogeneous bone marrow normal?
Consequently, heterogeneity of the spinal marrow is a normal phenomenon, especially in adolescence and middle age. Focal areas of red marrow may be a challenge to disclose its nature in some clinical scenarios and mandates making use of different MR pulse sequences to disclose its nature.
What is heterogeneity of bone marrow?
The bone marrow contains a heterogeneous population of macrophages at various differentiation stages with diverse phenotypes. Despite prior studies that perturbed macrophage differentiation and observed impaired red blood cell production, the specific identification of the island macrophage has remained elusive.
What causes tumour heterogeneity?
Tumour cells can also show heterogeneity between their expression profiles. This is often caused by underlying epigenetic changes. Variation in expression signatures have been detected in different regions of tumour samples within an individual.
Can an MRI tell if a lesion is benign or malignant?
Despite the superiority of MRI in delineating soft-tissue tumours, its ability is limited because most of these tumours have a non-specific appearance on MR images. Thus, it is often impossible using MR to determine whether the lesion is benign or malignant [5-8].
What is an example of heterogeneity?
For example, oil and vinegar, sand and water, and salt and pepper are all heterogeneous mixtures. Multiple samples of these mixtures will contain different proportions of each component. In statistics, heterogeneity is a vital concept that appears in various contexts, and its definition varies accordingly.
What’s another word for heterogeneity?
In this page you can discover 24 synonyms, antonyms, idiomatic expressions, and related words for heterogeneity, like: homogeneity, diverseness, diversification, multiformity, variety, variability, variation, diversity, heterogeneousness, variousness and polymorphism.
What is diffusely heterogeneous thyroid?
Heterogeneous echogenicity of the thyroid gland has been associated with diffuse thyroid disease and benign and malignant nodules can coexist with diffuse thyroid disease. Underlying heterogeneous echogenicity might make it difficult to differentiate between benign and malignant nodules on US.
What does diffuse heterogeneous marrow signal mean?
What causes heterogeneous bone marrow?
The myriad causes of bone marrow signal alteration include variants of normal, marrow reconversion, tumor (myeloproliferative disorders, metastatic, or primary), radiation, fracture, degenerative change, infection, inflammatory arthritis, and osteonecrosis.
What is diffuse inhomogeneity?
Inhomogeneous uterus texture refers to the appearance of focal masses giving a nonuniform heterogeneous surface of the uterus exterior wall, according to National Center for Biotechnology Information. The two most common causes of inhomogeneous uterus are uterine fibroids and adenomyosis. Uterine fibroids are benign tumors of muscular or fibrous tissue that develop on the outer endometrial uterine wall, states NCBI.
Is SS heterogeneous?
The members of Seamus the Cat’s gang are homogeneous in the sense that they are all felines, but heterogeneous in their outlooks and ideas for raiding Ye Olde Fish & Seafood Shoppe which can lead to a contentious atmosphere.
What does locus heterogeneity mean?
Locus heterogeneity refers to mutations in different genes at different chromosomal loci that cause an identical phenotype.
What is a heterogeneous enhancing mass?
Internal enhancement of masses can be described as homogeneous or heterogeneous. Homogeneous enhancement is confluent and uniform ( Fig. 8 ). Heterogeneous enhancement is non-uniform with areas of variable signal intensity (SI) ( Fig. 9 ).