What is an SSRI drug?
Selective serotonin reuptake inhibitors (SSRIs) are a widely used type of antidepressant. They’re mainly prescribed to treat depression, particularly persistent or severe cases, and are often used in combination with a talking therapy such as cognitive behavioural therapy (CBT).
What are the side effects of sertraline?
Sertraline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- nausea.
- diarrhea.
- constipation.
- vomiting.
- difficulty falling asleep or staying asleep.
- dry mouth.
- heartburn.
- loss of appetite.
How much sertraline can I take?
Adults—At first, 50 milligrams (mg) once a day, taken either in the morning or evening. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day.
How does an SSRI work?
How SSRIs work. SSRIs treat depression by increasing levels of serotonin in the brain. Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells (neurons). SSRIs block the reabsorption (reuptake) of serotonin into neurons.
What SSRI is best for anxiety?
Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed to treat social anxiety disorder. The only SSRIs that are currently FDA-approved for this condition are sertraline (Zoloft) and immediate- and extended-release paroxetine (Paxil, Paxil CR).
How do SSRI make you feel?
Common side effects of selective serotonin reuptake inhibitors (SSRIs) and serotonin-noradrenaline reuptake inhibitors (SNRIs) can include: feeling agitated, shaky or anxious. feeling and being sick. indigestion and stomach aches.
What’s the best SSRI for anxiety?
Should I take SSRI for anxiety?
Selective serotonin reuptake inhibitors (SSRIs), which were designed to treat depression, are also effective for many anxiety disorders. They have revolutionized the treatment of anxiety, replacing chronic use of benzodiazepines (BZs). SSRIs are effective for OCD, PDs, phobias, PTSD, and GAD (see Table I).
What is Desmethylsertraline (DMS)?
Desmethylsertraline ( DMS ), also known as norsertraline, is an active metabolite of the antidepressant drug sertraline. Like sertraline, desmethylsertraline acts as a monoamine reuptake inhibitor, and may be responsible for some of its parent’s therapeutic benefits.
Is desmethylsertraline an inhibitor of the serotonin transporter?
Desmethylsertraline, a metabolite of the antidepressant drug sertraline, was compared with sertraline for its ability to produce effects characteristic of inhibitors of the serotonin transporter in vivo.
Is desmethylsertraline a monoamine reuptake?
Like sertraline, desmethylsertraline acts as a monoamine reuptake inhibitor, and may be responsible for some of its parent’s therapeutic benefits.
What is the half life of N-desmethylsertraline?
N-desmethylSertraline has a plasma terminal elimination half-life of 62 to 104 hours. Both in vitro biochemical and in vivo pharmacological testing have shown N-desmethylSertraline to be substantially less active than Sertraline.