What does calcified splenic granulomas mean?
Overview. A calcified granuloma is a specific type of tissue inflammation that has become calcified over time. When something is referred to as “calcified,” it means that it contains deposits of the element calcium. Calcium has a tendency to collect in tissue that is healing.
What do calcifications in the spleen mean?
Diffuse punctate calcifications of spleen are seen in brucellosis (associated with suppurating lesions), tuberculosis, pneumocystis jiroveci (commonly associated with kidney and lymph node calcifications), candidiasis, histoplasmosis (larger lesions and usually more than six in number), and amyloidosis (along with …
What causes spleen calcification?
The causes of splenic calcification are numerous; histoplasmosis (Histoplasma capsulatum, predominately found in soil around the Mississippi river), tuberculosis, brucellosis (Brucella abortus), candidiasis, Pneumocystis jiroveci and sickle cell disease.
What does granulomas in the spleen mean?
Splenic granulomatous disease refers to sequelae arising from granulomatous infection-inflammation of the spleen. They are a result of: infective. splenic tuberculosis. splenic histoplasmosis.
What causes calcified splenic granulomas?
Calcified splenic granulomas are a common incidental finding, most commonly resulting from tuberculosis or histoplasmosis and less commonly from Pneumocystis carinii pneumonia or brucellosis [29, 30]. A risk factor for many of these infections is HIV infection.
What causes splenic granulomas?
Splenic granulomas present as single or multiple hypodense lesions on CT. These lesions are usually caused by M. tuberculosis infection and very rarely due to MAC. Splenic granulomas may be seen in association with disseminated MAC infections.
What causes spleen granulomas?
Are calcified granulomas cancerous?
Calcified granulomas are almost always benign. However, less commonly, they can become surrounded by a cancer tumor. Your doctor may also perform additional tests to determine what has caused the granulomas to form.