What is a perivascular lymphocytic infiltrate?
Perivascular lymphocytic infiltration therefore has been identified in a variety of systemic vasculitides affecting small, medium, and large vessels and also is a characteristic feature of both acute and chronic forms of dermatitis.
What can cause perivascular dermatitis?
|Epidermal changes||Differential diagnosis|
|– vacuolar – lichenoid||Erythema multiforme (Fig. 3) Drug rash Pityriasis lichenoides Lichen planus (Fig. 3) Mycosis fungoides Drug eruption|
|Without epidermal involvement||Lupus tumidus Polymorphic light eruption|
|Spongiosis||Arthropod reaction Photodermatitis|
What is an infiltrative disorder of the skin?
Jessner lymphocytic infiltrate is an uncommon skin condition that presents as non-scaly red patches and lumps on the face, neck and upper back. They are usually painless and do not itch. Lesions may go through periods of remission and exacerbation over months or years.
How do you treat perivascular lymphocytic infiltrate?
A diagnosis of Jessner lymphocytic infiltration of the skin was made. Treatment with intralesional corticosteroids every 4 weeks and oral hydroxychloroquine resulted in resolution after 4 months of therapy, thus far with no recurrence.
What is perivascular dermatitis?
Perivascular dermatitis. Inflammatory cells are clustered around blood vessels. In superficial perivascular dermatitis the deeper dermal vessels are unaffected; in superficial and deep, all are affected. Lichenoid dermatitis.
How do you get rid of perivascular dermatitis?
- Applying to the affected skin corticosteroid creams, gels or ointments.
- Applying to the affected skin certain creams or ointments that affect your immune system (calcineurin inhibitors)
- Exposing the affected area to controlled amounts of natural or artificial light (phototherapy)
What is lymphocytic dermatitis?
Lymphocytic infiltrate of Jessner is a skin condition characterized by small, red, bumps on the face, neck, and upper back. The bumps usually last for several months or longer and can enlarge to create a red plaque. Typically, there are no other symptoms, although rarely, individuals may experience burning or itching.
What is atypical lymphocytic infiltrate?
Atypical lymphoid infiltrates occurring in the setting of connective-tissue disease (CTD) comprise malignant neoplasms of B-cell or T-cell phenotypes and various reactive lymphoid hyperplasias, such as myoepithelial sialadenitis, lymphocytic thyroiditis, and lymphocytic interstitial pneumonitis.
What is perivascular inflammation?
A nonspecific finding consisting of the “cuffing” of lymphocytres around blood vessels, which occurs in various conditions—e.g., dermatomyositis, polyarteritis and other vasculitides.
What is chronic lymphocytic inflammation?
Summary. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a treatable inflammatory disease of the central nervous system. Specifically, it is a type of encephalomyelitis, which is a general term describing inflammation of the brain and spinal cord.
What is lymphocytic inflammatory infiltrate?
Lymphocytic infiltrate of Jessner is a rare skin condition that may be characterized by non-cancerous (benign) buildup of white blood cells, which present as lesions or lumps on the skin.
What is a perivascular lymphohistiocytic infiltrate?
Histologically, a perivascular lymphohistiocytic infiltrate is present in the superficial and sometimes deep dermis (Figs 8.29, 8.30 ). 25–27 A characteristic, but not uniformly present feature, is papillary dermal edema, which is often marked.
What is perivascular lymphocytic dermatitis?
Perivascular lymphocytic dermatitis is an inflammation in the skin which has been infiltrated by lymphocytes, a type of white blood cells. There isn’t much difference between perivascular dermatitis and other types of dermatitis really; it’s just that this one occurs near the blood vessels, caused by irritation to the skin or allergens.
What is a superficial perivascular inflammatory infiltrate?
Inflammatory dermatoses without epidermal changes The inflammatory skin dermatoses without epidermal changes are manifested histologically by a superficial perivascular inflammatory infiltrate (PVI). This reactive pattern is induced by many conditions.
What is the pathophysiology of PVI with lymphoplasmacytic infiltrate?
PVI with lymphoplasmacytic infiltrate. A prominent plasma cell component of the inflammatory infiltrate may be seen adjacent to an area of trauma, ulceration, or scar. It is also seen in cases of rosacea, secondary syphilis, and erythema chronicum migrans, which is pathognomonic of Lyme’s disease.